Abstract

THYROID DISORDERS WITH SPECIAL REFERENCE TO HYPOTHYROIDISM: A REVIEW

*Kanishkar P. R., Sabapathi P.

ABSTRACT

One clinical condition that primary care doctors frequently see is hypothyroidism. Infertility, dyslipidaemia, hypertension, cognitive decline, and neuromuscular dysfunction can all be consequences of untreated hypothyroidism. One in 300 Americans may have hypothyroidism, according to data from the National Health and Nutrition Examination Survey. Levothyroxine, a synthetic version of tetraiodothyronine, replaced thyroid extract therapy in the 1970s. There hasn't been any significant advancement in hypothyroidism therapy since then. There is disagreement about the biological definition of subclinical hypothyroidism. Thyroid gland autoimmune damage, prior thyroid surgery, and radioiodine treatment are major causes of hypothyroidism. Several drugs, such as lithium, amiodarone, and cytokines, frequently cause hypothyroidism. Congenital hypothyroidism that goes away on its own within the first few months or years of life is known as transient congenital hypothyroidism (TCH). There are currently few accurate indicators that indicate TCH at diagnosis, and the diagnosis is made when levothyroxine medication is stopped at the age of three. To examine hypothyroidism, a prevalent ailment in primary care, including its causes, consequences, diagnosis, and available treatments, such as levothyroxine, while emphasizing areas that require further development.

Keywords: Hypothyroidism, Thyroid Disorders, TSH (Thyroid Stimulating Hormone), T3 and T4 hormones.