Abstract

FAST DISSOLVING TABLETS – A REVIEW

*A. Kailash Kumar, Hemant K.S. Yadav.

ABSTRACT

Novel Drug Delivery Systems (NDDS) aim for designing dosage forms, convenient to be manufactured and administered, free of side effects, offering immediate release and enhanced bioavailability, so as to achieve better patient compliance Oral delivery is currently the gold standard in the pharmaceutical industry where it is regarded as the safest, most convenient and most economical method of drug delivery. Fast dissolving tablet is considered to allow administration of an oral solid dose form in the absence of water or fluid intake. Such tablets once placed on the tongue it readily dissolve or disintegrate in the saliva without chewing or water within less than 60 seconds. Fast- or mouth dissolving tablets have been formulated for paediatric, geriatric, and bedridden patients and for active patients who are busy and traveling and may not have access to water. This review includes requirements for fast disintegrating tablets, salient features, advantages, limitations, challenges in formulation, various technologies developed for fast disintegrating tablets, patented technologies, evaluation methods and various marketed products.

Keywords: Disintegration, Tablet, oral delivery.