Abstract

IN-VITRO ANTI- INFLAMMATORY ACTIVITY OF COMBINED METHANOLIC EXTRACTS OF TERMINALIA CHEBULA AND ALLIUM SATIVUM

T. Kalpana*, M. Rama Lakshmi, P. Mounica, M. Bindu, V. Surya Kumari and K. Radha

ABSTRACT

The combine bi- herbal methanolic extract made up of equal quantities of Terminalia chebula and Allium sativum. The combined bi- herbal methanolic extract was evaluated for its individual methanolic extracts of Terminalia chebula and Allium sativum. The extracts were screened for anti- inflammatory activity by Human red blood cell membrane stabilization method (HRBC). Paracetamol was taken as reference drug. Results revealed that the bi-herbal methanolic extract possesses significant anti- inflammatory activity at 200μg/ml. The individual methanolic extract of Allium sativum showed more activity when compared to that of the Terminalia chebula. The plant extracts showed dose dependent activity.

Keywords: Terminalia chebula, Anti- inflammatory, Allium sativum, Combined, Human red blood cell membrane stabilization.