Abstract

DE-PRESCRIPTION: A PROSPECTIVE OBSERVATIONAL STUDY IN THE INPATIENTS SETTING OF A TERTIARY CARE HOSPITAL

Aida Mary Joseph*, Aleena Prakash, Shalin Elsy Varghese, Hemaletha Selvaraj, Sheik Haja Sherief and Thangavel Shivakumar

ABSTRACT

Background: De-prescribing is the process of purposely stopping a medication or reducing its dose to develop the person’s health or reduce the risk of ADEs. Objectives: To objectives of the study was to identify and evaluate the de-prescribing medications among inpatients with co-morbidities and assess the patient adherence and improve the quality of life. Methods: This prospective observational study was carried out in a tertiary care hospital in Bangalore during the period of March 2018 to May 2018. Results: In this study out of 100 patients, 32 patients had undergone De-prescription and 68 patients hadn’t. The parameters evaluated in the study include patient’s age group, gender, co-morbid conditions, adherence to de-prescription and no de -prescription. The distribution based on age group was categorised into four includes 20-35, 36-50, 51-65 and above 65 years. Increased number of de-prescription was identified in the age group above 65 years .i.e 71.88% with de-prescription and 42.65% without de-prescription. Among the co-morbid conditions, hypertensive patients undergone greatest number of de-prescription (14) followed by CAD/IHD (8) and DM.(5) Conclusion: This study concluded that de-prescriptions were occurred to be more among elderly patients when compared to other age group. Elderly patients are suffered with multiple co-morbid conditions which may lead to polypharmacy.

Keywords: De-prescription, No de-prescription, Polypharmacy, Co-morbidities, Elderly patients.