Photo Gallery

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from  7.454 to 7.632  due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • WJPPS APRIL ISSUE PUBLISHED
  • APRIL 2021 Issue has been successfully launched on 1 April 2021.

Abstract

ENDORPHIN- NATURAL PAIN KILLER

Archana Sharma*, Ankur Sood, Neerupma Dhiman

ABSTRACT

Endorphin consists of two parts: endo and orphin; these are short forms of the words endogenous metersorphine which means "a morphine-like substance which is produced by the human body". The Endogenous Opioid system includes a large number of opioid peptides that are ligands for numerous types of opioid receptors. Three distinct families of endogenous opioid peptides have been well characterized- Endorphins, Enkephalins and Dynorphins. The three main types of opioid receptor are . Enkephalins interact with the δ receptor, Dynorphins interact with the receptor and Endorphins bind to both μ and δ receptors with comparable affinity. More recently, two additional short peptides, Endomorphin-1 and Endomorphin-2 that display a high affinity and selectivity for μ opioid receptors have been identified. But one of the main opioid peptide is the Human β- endorphins which have analgesic action. In this review we know about β- endorphins, its mechanism of action, & its different analogs with structure activity relationship.

Keywords: opioid, Enkephalins and Dynorphins.


[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More