A PROSPECTIVE STUDY ON PRESCRIBING PATTERNS OF ANTIPLATELET DRUGS
Bimal Sah*, Shubhekshya Bhandari, Ajay Yadav, Shiv Kumar Yadav, Dr. Dharshini N
M, Mrs. Mahadevamma L, Mr. Ramesh C.
ABSTRACT
Background: Antiplatelet agents are well recognized for their beneficial impact that reduces the ability of platelets to engage in thrombus formation. They do so by reducing the ability of platelets to aggregate together and also by inhibiting other aspects of platelet function that collectively contribute to thrombus formation. Platelet function is inhibited by agents that act directly on platelets to reduce their function and also by the rapid removal of platelet activating agents. Objectives: To access the prescription usage of antiplatelet drugs. Methodology: This was a Prospective and Observational study carried out for a period of 06 months at Apollo Multi-Speciality Hospital, Bengaluru. Patients of either sex and above 10 years of age, irrespective of all the departments were included. Selection of patients was based on inclusion and exclusion criteria. Results: Total of 151 patients were enrolled in the study in which the maximum number of patients were under high socio-economic status. The mostly preferred therapy was combinational therapy and maximum prescribed antiplatelet drugs were between the age group of 51-60 years. The maximum drug interaction were seen with Ticagrelor and Aspirin in Antiplatelet drug. Aspirin were considered as cheapest drug whereas the Ticagrelor were considered expensive drug. Conclusion: Antiplatelet usage vary with individuals according to their disease conditions to minimize the adverse drug reaction, drug-drug interaction, cost of the treatment and other medication errors. The mostly prescribed antiplatelet drug was aspirin and monotherapy was highly preferred then the combinational therapy.
Keywords: Prescription usage, Antiplatelet, Drug-drug interaction.
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