Abstract

A STUDY ON SELECTED PARAMETERS RELATED TO URINARY TRACT INFECTIONS AND RENAL STONE FORMATION

*Mohemid M Al-Jebouri and Zydoon H Ali

ABSTRACT

Background:The risk factors of obesity and their correlation with many chronic disease like cardiovascular diseases, renal disease, and some metabolic disorder diseases like hyper lipedemia. Hypertension is also a leading cause of human cardiovascular and might be one of the disorders leading to renal diseases. Aldosterone is a hormone regulates the amounts of electrolytes in the body. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney.Methods: The number of patients with renal stones were 100 recruited from November 2012 until June 2013.Urine culture and renal stones collected from patients were carried out. Serum sodium, potassium, chloride, calcium ,cholesterol, triglycerides, prostatic antigen and immunoglobulin A were also estimated and correlated with obesity and hypertension of patients studied. Results: It was found that 46% of patients were hypertensive. The frequency of patients number with family history of renal stone was 28%.More than 50% of the patients were with >30 Kg/m2 body mass index(BMI).Ony 9% of the patients revealed urinary tract infection(UTI). It was concluded that 46% of the patients with renal stones were hypertensive. In the present at study serum values like sodium(Na+2),potassium (K+2), chloride(Cl+2),calcium(Ca+2) , cholesterol, triglyceride ,prostate specific antigen (PSA) , immune globulin A (IgA) and aldosterone hormone were done and these variables were distributed according to sex , age , body mass index ,residence and blood pressure combined with UTI .The values of these parameters were variables and sometimes showed significant differences utilizing relevant statistical analyses. Conclusion: The obesity of the patients studied was associated with increased values above the normal serum range of cholesterol,triglycerides,sodium, chloride and IgA with different frequencies.Potassium , chloride and PSA levels highly elevated in case of hypertensive patients.IgA and PSA increased above the normal levels of serum in patients with urinary tract infections.

Keywords: IgA,aldestrone,cholestrol,trichlycerides,hypertension,obesity,UTI,urolithiasis, serum ions.