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Abstract

DECREASED AMNIOTIC FLUID GLUCOSE LEVEL AND WEIGHT GAIN OF CHICK EMBRYO BY ALCOHOLIC EXTRACT OF GYNURA PROCUMBENS

Pritam Goswami, Sk. Swaif Ali, Joydeep Khanra, Anamika Basu, Sayak Ghosh and Satadal Das*

ABSTRACT

Patients suffering from diabetes mellitus are gradually increasing throughout India. The burden was 31 million in the year of 2000 and within 2030 it is expected to rise more than 100 per cent to reach 79.4 million whereas the global load is expected to reach 360 million or more by that time. This disease is associated with major complications like ischemic heart disease, retinopathy, nephropathy, neuropathy etc. So there is a scope to search newer drugs to control the disease effectively. Gynura procumbens which belongs to the family Asteraceae has been claimed to have anti-hyperglycaemic, anti-cancer and anti-inflammatory activities. In this experiment amniotic glucose lowering activity of Gynura procumbence leaf extract was tested in alloxan treated chick embryo. The results of this experiment revealed that the leaf extract is not only capable of reducing the amniotic fluid glucose level, but it has got also capability of increasing body weight of the chick embryo. Thus this plant extract may prove to be an ideal medicine for underweight diabetes mellitus patients in future days to come.

Keywords: Gynura procumbens, chick embryo, glucose lowering activity, alloxan, weight gain.


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