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Abstract

REGIONAL OCCURRENCE, ANTIBIOGRAM- RESISTOGRAM AND VIRULENCE PATTERNS OF CARRIER - DERIVED VANCOMYCIN RESISTANT STAPHYLOCOCCUS AUREUS (VRSA)

Beerbal Kumar B., Panneer Selvam K.*, Nambirajan G., Rajan S. and and Reshma A.

ABSTRACT

Vancomycin resistant Staphylococcus aureus (VRSA) are the most important drug resistant pathogens of public health concern and are currently reported frequently compared to earlier times. Though vancomycin has been considered as the drug of choice for the treatment of methicillin resistant S. aureus infections, the therapy became a challenge after the emergence of vancomycin staphylococcal isolates. Against the fact that S. aureus cause serious diseases from surgical wound infections to blood stream infections, their reported carriage by healthy persons, emerging resistance to a significant number of antibiotics including vancomycin, the treatment of such infections has become more difficult. As regular screening of healthy persons for S. aureus with special reference to VRSA carriage and determination their antibiotypes would benefit the health care providers to prevent/ control and treat infections by VRSA promptly, the screening carried out during the present study brought out the fact that as much as 15 (5.5%) of 272 carrier- derived S. aureus were identified to be resistant to vancomycin possessing a diverse antibiotic susceptibility patterns/ virulence features.

Keywords: Carrier- derived VRSA, susceptibility testing, antibiotypes, virulence.


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