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Abstract

A NEW TOOLS FOR TRANSDERMAL DRUG DELIVERY SYSTEM: AN INSIGHT

*Kathiravan P., Balaji P. and Matheshwaran M.

ABSTRACT

Transdermal drug delivery systems are polymeric patches containing dissolved or dispersed drug that deliver therapeutic agent at a constant rate through skin. Transdermal delivery has made an important contribution to medical practice but has yet to fully achieve its potential as an alternative to oral delivery and hypodermic injections. The principle of TDDS is that they could provide sustained drug delivery (and hence constant drug concentration in plasma) over a prolonged period of time. TDDS can be designed to input drug at appropriate rate to maintain plasma-drug levels for therapeutic efficacy. Ultimately the success of all the transdermal system depends on the ability of the drug to permeate skin in sufficient quantities to achieve its desired therapeutic effect. This review article provides a detailed study of transdermal that is advantage, disadvantages, mechanism, factors affecting skin permeation and types. This article also focuses on the application and future approaches of transdermal drug delivery system.

Keywords: Transdermal, skin, delivery system.


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