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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: APRIL ISSUE PUBLISHED

April Issue has been successfully launched on 1 April 2024.

Abstract

DEVLOPEMENT AND VALIDATION OF STABILITY INDICATING RP-HPLC METHOD FOR SECNIDAZOLE GRANULES

Digambar Ashok Nagare*, Dr. Vipul P. Patel, Sima Gosavi and Tushar N. Deore

ABSTRACT

Objective of the present work is to develop and validate a simple, cost effective, sensitive and fast RP-HPLC method for the analysis of Secnidazole Granules. A Waters HPLC system with Inertsil ODS-3V, C18, 150 mm, 5μm column is employed for the analysis using 0.01 M Potassium Dihydrogen Orthophosphate Buffer Solution, Acetonitrile And Methanol in the ratio of (70:25:5 v/v) as mobile phase. Signal from Secnidazole is detected at 228 nm by UV Spectrophotometer. The proposed method is fully validated and found to be linear over a workable drug concentration, accurate, precise and robust. This fast and inexpensive method and also this method is HPLC Equivalent to UPLC. It is suitable for research laboratories as well as for quality control analysis in pharmaceutical industries.

Keywords: Secnidazole, RP-HPLC, Waters system , validation etc.

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