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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.485

ICV : 84.65

WJPPS Citation

	All	Since 2020
Citation	6651	4087
h-index	26	21
i10-index	174	83

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Abstract

COMPARATIVE ANTIULCER ACTIVITY OF PULP & SEED OF ETHANOLIC EXTRACTS OF CUCUMIS MELON (LINN) IN RATS

Veer Bala* and Nidhi Tyagi

ABSTRACT

The present study was undertaken to investigate antiulcer effect of ethanolic extracts of pulp & seed of Cucumis melon L. in Wistar rats. Ethanolic Pulp extract of Cucumis melon L. was administered to experimental rats at doses of 200 and 400 mg/kg. & ethanolic seed extract was administered at doses of 200 and 400 mg/kg. Standard drug was Ranitidine (50mg/kg) while normal saline (0.9%) was used as control. The antiulcer effect of the extracts was evaluated measuring different parameters like free acidity, total acidity, ulcer index, ulcer score, gastric secretion and pH of the gastric juice. In addition, total acidity and free acidity were also reduced significantly (**P

Keywords: Herbal medicine, Cucumis melon L., Ethanolic extract, Antiulcer activity.

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