Abstract

PHARMACOGNOSTIC ACTIVITIES OF UNDER GROUND ROOTS OF FICUS BENGHALENSIS LINN

Hikmat Ullah Jan ?, Navid Khan, Muhammad Siraj and Amjid Uzair

ABSTRACT

Medicinal plant can provide the diverse useful tools for treating of many altered diseases. The traditional medicine can be based on hundreds of the year of scrutiny and credence which predicate the stretch and expansion of many modern medicines. As Pharmacognosy is the study of drugs from plant and animals in the form of tinctures, teas, powder and other herbal formulation. The current study evaluated the preliminary phytochemical analysis of the methanol extracts showed the presence of carbohydrates, flavonoids, amino acids, steroids, saponins and tannins. The current study evaluated pharmacognostic analgesic, tail immersion, paw reading, antispasmodic, acute toxicity and muscle relaxant activities of Ficus benghalensis Linn. Underground root extracts in Ethanol, Methanol and Distilled water was applied on Albino mice of Swiss origin. The analgesic activities was done by using acetic acid induced activity, Tail immersion and Paw readings with radiant heat hot plate method, Muscle relaxant activity by Traction test and acute toxicity activities. All the extracts showed excellent potential against analgesic activity also in Tail immersion and Paw readings activities at 200 mg/kg dose as compare to the standard drug by using an animals Albino mice. Underground root extract showed active charcoal movement about 18.33±2.08*, 18±1.73*and 18.66±1.15* at 200mg/kg dose. Ethanolic extract of underground root of Ficus benghalensis Linn. were found to be more potent 7.66±0.57* and 7±1*. Underground root ethanolic extract was effective out of the three extracts in each activity and was dose dependent.

Keywords: Ficus benghalensis Linn, Analgesic, Antispasmodic, Acute toxic, Muscle relaxant, Tail immersion, Paw reading.