Abstract

PHYSICO – PHYTO CHEMICAL SCREENING AND ANTIUROLITHIATIC POTENTIAL IN ALBINO RATS FOR PEDALIUM MUREX L.

T. S. Bhuvaneswari*, T. Thirugnanam and V. Thirumurugan

ABSTRACT

Kidney stone disease is a common disorder estimated to occur in approximately 12% of the population, with a recurrence rate of 70-81% in males, and 47-60% in females. Epidemiological data suggest that 60-80% of stone is composed mainly of calcium oxalate. The use of plant products with claimed uses in the traditional systems of medicine assumes importance. Urolithiasis is the condition where urinary calculi are formed or located anywhere in the urinary system or the process of forming stones in the kidney, bladder and ureters. Pedalium murex.L is a member of sesame family, Pedaliaceae. In English it is known as Bara-gokhru and in Tamil it is known as Anai-Nerinji. In this study organoleptic character, fluorescence characters, physico chemical studies, different extract values in various solvents, and qualitative phytochemical analysis are seen for the study plant Pedalium murex.L.Biochemical analysus in urine for calcium oxalate levels and on serum urea and creatinine levels on glycolic acid induced urolithiasis in albino rats are seen. The values are statistically expressed. The results are proven that study plant has antiurolithatic property which conforming claimed uses in the tradiational medicinal system.

Keywords: Padalium murex.L, Physico-Phyto chemical screening, antiurolithiasis.