Abstract

TO DEVELOP UV-VISIBLE SPECTROSCOPIC METHOD FOR ESTIMATION OF METFORMIN HCL IN TABLET DOSAGE FORM

Bhushan R. Pawar, Mahesh B. Thorat, Nilam B. Pawar, Monika D. Karanjkar, Tejaswini S. Karande, and Tushar H. Katkar*

ABSTRACT

A simple analytical spectroscopic method for estimation oeveloped for Metformine HCl in tablet dosage form. This method is rapid, sensitive, & specific UV-Visible method was Metformine HCl in tablet dosage form, The analysis complied with Beer’s law in the concentration range 8-13μg/ml at λmax 233nm for Metformine HCl. For this method Distlled Water is used as solvent. The validation of Metformine HCl in tablet dosage form was performed as ICH guidlines for linearity, precision, accuracy, limit of detection, limit of quantitation. This proposed method was successfully applied for the quantitative determination of Metformine HCl in tablet dosage form.

Keywords: Metformine HCl(MET), LOQ, LOD.