Abstract

A COMPARATIVE IN VITRO ANTIFUNGAL STUDY OF CAMELLIA SINENSIS MEDIATED IRON NANOPARTICLES

S. Thangapandiyan*, A. S. Alif Alisha and P. Sufaija

ABSTRACT

Nanotechnology in medicine is going to have a wide impact on the survival of the human race. The objective of the nanotechnology is to create the eco-friendly designs with nanotechnology and use it to reduce health and environmental hazards by seeking methods to replace present applications with green nanotechnology products. In the present study, we report a simple green method for the synthesis of iron nanoparticles using Camellia sinensis leaf extract. The synthesized iron nanoparticles were characterized by visual inspection UV, XRD, EDS and SEM. The antifungal activity of iron nanoparticles was evaluated using agar-well diffusion method. The maximum zone of inhibition for Camellia sinensis mediated iron nanoparticles obtained against Fusarium oxysporum (37.33 ± 1.15 mm) followed by Aspergillus fumigatus (34.33 ± 1.15 mm), Fusarium solani (29 ± 0.57 mm) and Aspergillus flavus (24.33 ± 1.15 mm). Results obtained that the Camellia sinensis mediated iron nanoparticles showed excellent antifungal activity on selected pathogens than the Camellia sinensis plant extract alone.

Keywords: Nanotechnology, Camellia sinensis, Iron nanoparticle, Antifungal activity, Zone of Inhibition.