Abstract

ANTIBACTERIAL & ANTIFUNGAL POTENTIALITY OF RICINUS COMMUNIS & COLEUS FORSKOHLII ON SOME HUMAN PATHOGENIC MICROORGANISMS

Kamal E. M. El Kahlout, Abboud Y. El Kichaoui, Ashraf A. Shafei, Farida N. Mosleh, Sabreen El Mazloom, Ismail M. El Quqa and Mahmoud W. El Hindi*

ABSTRACT

The objective of the present study was to explore the antibacterial and antifungal activity of two plant extracts (Ricinus communis & Coleus forskohlii) against some selected pathogen (Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae and candida albicans) using microdilution method (MIC) at different concentrations (100-0.195mg/ml) and Disc diffusion method (200 mg/ml). The extracts of plants were prepared using Soxhlet apparatus for 8 hr. The results of this study proved of the water extract of Ricinus communis showed maximum zone of inhibition against E. coli and the lowest minimum inhibitory concentration against all tested microorganisms. Coleus showed powerful antimicrobial activity against Gram positive and Gram negative bacteria. The water extract of Coleus showed maximum zone of inhibition against k. pneumonia.

Keywords: Antibacterial & antifungal, microdilution method (MIC), Disc diffusion method, Ricinus communis, Coleus forskohlii.