Abstract

A PHARMACEUTICO – ANALYTICAL STUDY OF VARUNA SHIGRU GUGGULU- AN ANUBHUTA YOGA

Dr. Joyal Patel*, Dr. Sushant Sud, Dr. T. S. Dudhamal and Dr. Kalpesh Dattani

ABSTRACT

Ayurveda is a highly evolved and codified system of life and health science based on its own unique and original concept and fundamental principles. The Aushadha Kalpana is prepared by different pharmaceutical processing techniques applied to the crude drugs to get the desired therapeutic effect. This processing results in transformation of good pharmacological action to that of substance. In context of present study one of the Guggulu preparations is selected, which is not mentioned in classics namely Varuna Shigru Guggulu (VSG) prepared with some modifications. Aims and Objectives: To developed standard operative procedure for preparation of genuine sample of VSG, to find out the unwieldy in the preparation, to analyze the VSG for safety, and purity. Material and Methods: To full fill the above objectives of the present study all the parameters were taken according to “Protocol of testing ASU medicine published by PLIM, Dept. of AYUSH, Ministry of health and family welfare Govt. of India. Parameters like organoleptic properties, Physico-chemical analysis, HPTLC, etc. were used for analysis of sample of test drug which were prepared by using Kuttana (pounding) method. Results and Conclusion: Presence of low amount of loss on drying (13.4%w/w) leads to decrease decomposition and enhance the shelf life and therapeutic value of the same. Low Ash Value (15.027%) and Low Acid insoluble Ash (2.155%) determines the presence of low adherent dirt as well as sand particles. Microbial load was shown within limit results which refers safety profile of the samples. HPTLC finger print profile was developed for this sample can be used as a marker for later on samples.

Keywords: Varuna Shigru Guggulu, HPTLC, Pharmaceutico-Analytical study.