Abstract

SYNTHESIS AND SPECTREAL CHARACTERIZATION OF PYRAZOLINE DERIVATIVES FROM CHALCONE DERIVATIVES

Abdul-Wahab J.Al-Hamdany, Hashim J.Azeez and Eman M. Hassan*

ABSTRACT

The present research work describes the synthesis of new pyrazoline compounds and Chalcone derivatives. Synthesis of chalcones (1-9) were achived by condensation of diacetyl with substituted benzaldehyde in ethanolic sodium hydroxide (50%). The later compounds reacted with hydrazine hydrate (80%) in glacial acetic acid to yield 1,1'-(aryl -4,5-dihydro-1H-pyrazole-1,3-diyl)bis(ethan-1-one) (10-17). The characterization of the resulting products were confirmed by melting points, UV-Visible, FTIR, 1HMNR, 13C-NMR and Mass. (for some of them) spectral data.

Keywords: New Chalcones, Pyrazolines.