Abstract

A STUDY ON ASSESSMENT OF MULTIPLE DRUG RESISTANCE TUBERCULOSIS CASES IN ERODE DISTRICT UNDER RNTCP AND ITS PROPOSED CLINICAL PHARMACIST INTERVENTIONS

Alan James*, Rinto Paul Raju, Sophiya T. Varghese, Dr. K. P. Mohanraj, Dr. S Haja Sheriff, Apollo James and Dr. T. Sivakumar

ABSTRACT

The aim of our study is to assess the MDR TB cases in Erode district under RNTCP and to provide guidelines to the hospital administration regarding Tb and to evaluate the risk factors associated with Tb and provide proper counselling to the patients to reduce the impact of Tb among them. Methods: A bidirectional study on MDR Tb cases was conducted during the period of February 2016 – July 2016 at Government Head Quarters hospital under RNTCP in Erode district. Results: In our study, we collected 65 cases of MDR TB and it indicated that male (55.38%) patients were having more drug resistance as compared to female (44.61%)patients. We also concluded that smoking, alcohol consumption, diabetes, HIV is the major risk factors associated with the cause of emergence of Tb. Conclusion: Tuberculosis remains a worldwide public health problem which cannot be eradicated completely without proper adherence. HIV, cigarette smoking, alcoholism, diabetes, and poor adherence are major factors for development of MDR TB. In order to prevent the emergence of MDR TB, we must give patient information’s regarding the importance of treatment adherence. Apart from that accurate susceptibility testing is necessary to identify the MDR TB cases.

Keywords: Tuberculosis, Multiple Drug Resistance, Drug susceptibility testing, Centrifugation Based Nucleic Acid Amplification Assay.