Abstract

CONNECTION BETWEEN AGEING AND CANCER

*Ankur Sood

ABSTRACT

The risk of many chronic diseases increases when the peoples get older. The chronic diseases are increases due to common theories of ageing, such as mutation accumulation, wear and tear, and antagonistic pleiotropism etc. However, the risk of some chronic conditions (e.g. asthma, arterial hypertension) declines in the old. At first glance, it doesn’t look like that ageing and cancer have any relationship. The scientists have intrigued the relationship between cancer and ageing for decades. It has long been widely accepted that ageing is the single greatest risk factor for developing cancer. Ageing may increase or decrease the susceptibility of various tissues to initiation of carcinogenesis and usually facilitates promotion and progression of carcinogenesis. A number of events at the molecular, cellular, and physiologic levels are associated with ageing that influence carcinogenesis and subsequent cancer growth. Here we review the main points to understand the connection between the ageing & cancer.

Keywords: Chronic diseases, ageing, cancer.