Abstract

DRUG UTILISATION REVIEW OF CEPHALOSPORINS IN A TERTIARY CARE HOSPITAL – A RETROSPECTIVE STUDY

Arul B.*, Rangabashyam S. R., Kothai R., Bobby Mathew Thomas, Elavarasi M., Glory M. Abraham

ABSTRACT

Objectives: To assess the prescribing patterns of Cephalosporin in a Tertiary care hospital, to determine the frequency of drug usage of Cephalosporin antibiotics, to study the indications for which the drug was being prescribed and to identify therapeutic treatment, co-morbidity conditions in the patients. Methodology: A Retrospective study was conducted for a period of six months from November 2016- April 2017, in the various departments of a tertiary care hospital, Salem, Tamilnadu. Results: Cephalosporin Utilisation was evaluated in 150 patients in the various departments of the hospital. The present study involves 54% of males and 46% of females. Patients with the age group of 51-60 (52.67%) received the majority amount of Cephalosporins. The Culture sensitivity test was done in 26 patients. Cephalosporins were widely prescribed in the department of General Medicine (67.33%). Out of the 150 prescriptions only six were found to have drug-drug interactions. Conclusion: Cephalosporins especially third generation drugs were widely used when compared to second generation of drugs. The therapy provided in the prescriptions were efficacious but there is a need to emphasize to all prescribers encourage prescribing by generic name and to do the culture sensitivity tests more often so as to reduce the incidence of a grave danger i.e. antibiotic resistance.

Keywords: Cephalosporins, Drug utilization review, Rational drug use.