Abstract

REGENARATIVE EFFECT OF VANGA BHASMA IN CADMIUM CHLORIDE INDUCED TESTICULAR DAMAGE - AN EXPERIMENTAL STUDY.

Kavya Shree B. P.*, Shreeshananda Sharma and Manjula S. N.

ABSTRACT

Vanga bhasma is a metalic preparation that acts in cases of Sexual debility and Oligospermia, it boosts up dhatuagni’s and facilitates the nourishment of all the body tissues and thus augments ojas. Hence used in treatment of male infertility. The present work was undertaken to study the effect of Vanga bhasma on Cadmium Chloride(0.9% in normal saline) induced Testicular toxicity in Wistar rats. Vanga bhasma was administered for 30days and at the end of the study, blood samples, tissue samples and spermatozoans were collected and analyzed for various biochemical and histopathological parameters. Cadmium chloride produced testicular damage by exhibiting symptoms like shrinkage of Testis. Administering Vanga bhasma prevents oxidative stress, Apoptosis of testicular cells and helps in maintaining normal blood harmonal level(Serum Testosterone) and normal morphology of sperms. Here Ashwagandha churna is taken as a standard drug as it is most widely practised and in knowing superiority of Rasa Aushadis.

Keywords: Testicular toxicity, Vanga bhasma(VG), Cadmium chloride, Ashwagandha (AG).