Abstract

EVALUATION OF ANTIMICROBIAL ACTIVITY OF DIFFERENT SOLVENT EXTRACTS OF SAUSSUREA LAPPA

Abdalkareem Mohamed*, Mohammed Aldaw, Eman Ismail, Alyaa Abu algasim and Eithar Karar

ABSTRACT

Antimicrobial efficiency of S.lappa (root extracts) was examined using different kinds of solvents [Methanol, chloroform, and water] and tested against five human pathogens like Bacteria: Bacillus cereus, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Fungi: C.Albicans using disc diffusion method to evaluate the antimicrobial activity. The plant extracts showed significant activity against all pathogens except E.coli and P.s, but the alcoholic extract [methanolic extract] of S.lappashowed maximum zone of inhibition against S.aureus and B.subtilis (Table 2). The Spectrum of activity observed in the present study may be indicative that these plants could be possible source of new and effective herbal medicines to treat infections, hence justified the ethnic uses of S.lappa against various infectious diseases.

Keywords: Antimicrobial activity, medicinal plants, Disc diffusion method.