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Abstract

ANTI-CANCER ACTIVITY OF LEAF EXTRACT PREPARATION FROM IPOMOEA SEPIARIA AGAINST MCF-7 CELL LINE

Sudhakar Meesala* and DSVGK Kaladhar

ABSTRACT

Ipomoea is the largest genus with over 500 species in the flowering plant belonging to the family Convolvulaceae. Ipomoea sepiaria Koenig ex Roxb. is well known as Lakshmana in Sanskrit distributed throughout greater part of India. The anticancer activity of aqueous extract of Ipomoea sepiaria was investigated by MTT assay using MCF-7 cell line. The present experimentation showed that aqueous extract of Ipomoea sepiaria when subjected to different concentrations on MCF-7 cells showed IC50 cell inhibition at about 10μM for 48 hours and about 2μM for 72 hours.

Keywords: MCF-7, Ipomoea sepiaria, Anticancer activity.


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