Photo Gallery



News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from  7.454 to 7.632  due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • JUNE 2021 Issue has been successfully launched on 1 June 2021.



Sucharitha. M*, Anjali Devi.N, Vishnu Priya.P, Shyamala, JVC. Sharma


Valsartan, an angiotensin-receptor blocker (ARB) widely prescribed in variety of cardiac conditions like hypertension, diabetic nephropathy and heart failure. The biological half-life (3-6 hours) and maximum absorption in initial part of gastro intestinal tract of Valsartan favors development of gastro retentive floating dosage form. In the present study Valsartan floating tablets were prepared by effervescence method using sodium bicarbonate and citric acid as a gas generating agent. The tablets were formulated using direct compression technology by employing polymers like HPMC K4M, HPMC K15M, HPCM K 100M and Eudragit. The drug-excipient compatible studies were performed by FTIR, and the study revealed that there is no drugexcipient interaction. The prepared floating tablets were evaluated for various physicochemical parameters. The in-vitro drug release pattern of Valsartan floating tablets was fitted to different kinetic models which showed highest regression for zero order kinetics with Higuchi mechanism. Out of all formulations the one prepared with Eudragit was optimized based on desired sustained release time (24hrs) followed by acceptable swelling and floating properties.

Keywords: Valsartan, Floating tablets, HPMC, Eudragit, direct compression, sustained release.

[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More