Abstract

ANTICANCER ACTIVITY OF HERBO-MINERAL FORMULATION IN VITRO: A PRELIMINARY STUDY

Anita Mehta*, Dipti Patel, Kuntal Shah, Bhavini Shah, Jayesh Beladiya and Kiranj Chaudagar

ABSTRACT

Cancer is characterized by uncontrolled proliferation of cells with the potential to invade and metastasize. It is one of the leading causes of morbidity and mortality which affects the human population globally. Scientific and research interest is drawing its attention towards naturally-derived compounds as they are considered to have less toxic side effects compared to current treatments such as chemotherapy. The plant kingdom produces naturally occurring secondary metabolites which has been reported for its anticancer activities. In our study we have evaluated the anticancer activity of CYTOCRUEL a herbo minerals formulation which contain different plant extracts and minerals from the nature. The concentration dependent cell viability (MTT) assay of CYTOCRUEL was performed on the two different cancer cell lines that is MDA-MB-231(Breast cancer) and A549 (Lung cancer). The results of MTT assay CYTOCRUEL show dose dependent reduction in % of cell viability at 48 hour of treatment in both the cell lines as compared with normal control which suggests its effective use in treatment of cancer.

Keywords: Cancer, Herbo-mineral, Cytocruel.