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  • MARCH 2021 Issue has been successfully launched on 1 March 2021.

Abstract

ANALYTICAL TECHNIQUES USED IN QUALITY CONTROL OF DRUGS: REVIEW

Binu Varghese, Lakshmi V. V.* and Anjali Nair G.

ABSTRACT

Analytical chemistry has provided many of the tools and methods necessary for research in the other traditional areas of chemistry. An analytical technique is a method that is used to determine the concentration of a chemical compound or chemical element. There are a wide variety of techniques used for analysis, from simple weighing (gravimetric analysis) to titrations (titrimetric) to very advanced techniques using highly specialized instrumentation. .From the stages of drug development to marketing and post marketing, analytical techniques play a great role, be it understanding the physical and chemical stability of the drug, impact on the selection and design of the dosage form, assessing the stability of the drug molecules, quantization of the impurities and identification of those impurities. The pharmaceuticals would serve their intent only if they are free from impurities and are administered in an appropriate amount. To make drugs serve their purpose various chemical and instrumental methods were developed at regular intervals which are involved in the estimation of drugs. For this analytical instrumentation and methods play an important role. This review highlights the role of the analytical instrumentation and the analytical methods in assessing the quality of the drugs.

Keywords: Analytical Instruments, Titrimetry, Chromatography, Spectroscopy and Electrophoresis.


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