Photo Gallery

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from  7.454 to 7.632  due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • WJPPS FEBRUARY ISSUE PUBLISHED
  • FEBRUARY 2021 Issue has been successfully launched on 1 February 2021.

Abstract

“MICROBIAL REDUCTION OF KETONES AND ITS DERIVATIVES”

Pankaj Kumar Patel*, Dr. Anup Kumar, Sandhyavali M.S., Priyadarshini S.R., Dr. Ambrish Kumar Singh

ABSTRACT

Microbial reduction of ketones is gaining importance in synthetic chemistry as an alternative tool for the synthesis of enantiomeric alcohols. To date biocatalytic reduction of Acetophenone and its derivatives has been widely reported. We have made an attempt to screen some of the microorganisms which were obtained from culture collection centre as well as those isolated in our microbiology lab, for their potential and performance in reduction of ketones. Among the screened microorganisms, used for the reduction of Acetophenone and its derivatives, Aspergillus flavus, Aspergillus niger showed significant bioconversion where as Candida viswanathii and Sacchromyces crevisae exhibited the least conversion. As Aspergillus flavus showed maximum ability of bioreduction, it was considered for optimization. The parameter evaluated during optimization includes pH, temperature, and substrate concentration and incubation time. The optimization conditions at which maximum bioconversion was achieved where pH 7.6, temperature 300C, incubation time 48hours and substrate concentration 0.2ml (238.2mg).

Keywords: Acetophenone, p-chloroacetophenone, Aspergillus flavus, Aspergillus niger, Candida viswanathii, bioreduction, optimization.


[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More