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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2020
Citation	6651	4087
h-index	26	21
i10-index	174	83

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WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2025 Issue has been successfully launched on 1 NOVEMBER 2025.

Abstract

DEVELOPMENT OF HPLC METHOD FOR THE DETERMINATIONOF ZINC CARNOSINE

Aakash Sahu*, Abha Doshi and Bhosale Suryakant D.

ABSTRACT

A reverse phase HPLC method is developed for the determination of zinc carnosine in pharmaceutical dosage forms. Chromatography was carried out on a C18 column [250mm, 4.6m, 5μm] using a mixture of potassium di-hydrogen ortho phosphate buffer and Acetonitrile (76:24 v/v) as the mobile phase at a flow rate of 1 mL/min. Detection was carried out at 215 nm .The retention time of the drug was 5.700 min. The method produced linear responses in the concentration range 0.5 to 60 μg/mL of zinc carnosine. The LOD and LOQ values for HPLC method were found to be 1.29 and 3.90 μg/mL respectively. The method was found to be applicable for determination of the zinc carnosine.

Keywords: HPLC, Zinc carnosine, Estimation, validation.

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