WJPPS Citation

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • New Impact Factor
  • WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

  • WJPPS: MARCH ISSUE PUBLISHED
  • March Issue has been successfully launched on 1 March 2024.

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • Scope Indexed
  • WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

Abstract

ORGANIC NITROGENOUS COMPOUND INVOLVED IN LOCAL IMMUNE RESPONSES

Mohd. Gayoor Khan* and Dr. H. S. Chandel

ABSTRACT

Histamine is the major cause of allergy, urticaria, common cold, Hay fever, food allergy, and rhinitis. In today’s life it is necessary to know about the factors that increases histamine level in the body such factors are histamine containing food or food that inhibit the enzyme diamine oxidase. Stress is an another important factor that influence the histamine level in the body and that drugs that increases the histamine level in the body .The first generation antihistaminic drugs have certain side effects but also have some special property for example- promethazine is used to control pregnancy vomiting, sialorrhoea, tremor, morning sickness and cyproheptidine is having appetite stimulant activity. The first generations antihistaminic drugs are also available in the market the main cause of it is the muscarinic receptors activity of the first generation activity. The second generation antihistamines overcome the side effects that were caused by the first generation antihistaminic drugs mainly sedation. The second generation antihistaminic have a disadvantage that they are less effective to common cold, rhinitis due to lack of muscarinic activity. The second generations drugs (cetirizine) have property to inhibiting leukotriene C4 and D4 that are main cause of asthma The future aspect is to control the release of histamine in the body by H3 antagonists. The H3 antagonists also have antidepressant activities that overcome the stress factor.

Keywords: .


[Download Article]     [Download Certifiate]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More