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Abstract

DESIGN, DEVELOPMENT AND EVALUATION OF CURCUMIN LIPOSOMES

A.Maheswaran*, P.Brindha, AR.Mullaicharam, K.Masilamani

ABSTRACT

The purpose of this investigation was to design, develop and to evaluate the liposomal drug delivery system for curcumin, an herbal drug isolated from Curcuma longa. Liposomes were prepared by using phospholipid as carrier. Eight formulations (CL1 – CL8) were designed and prepared by varying the concentrations of phospholipids. All the prepared formulations were evaluated. The results showed that CL4 formulation was found to be best amongst other formulations.

Keywords: Curcumin, Curcuma longa, liposomes, phospholipid, bioavailability.


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