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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2020
Citation	6651	4087
h-index	26	21
i10-index	174	83

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WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2025 Issue has been successfully launched on 1 NOVEMBER 2025.

Abstract

INVESTIGATION OF ANTIBACTERIAL POTENTIAL OF ASCIDIAN, MICROCOSMUS EXASPERATUS (Heller, 1878) AGAINST HUMAN URINARY TRACT PATHOGENS

*G. Ananthan and K. Iyappan

ABSTRACT

The current investigation is based on the discovery of novelantibacterial from new sources which have not been amply exploited.The main objectives of this work was to ascertain the antibacterialefficacy of a marine ascidian, Microcosmus exasperatus, collectedfrom Palk Bay, Southeast coast of India, against selected urinary tractpathogens. The crude methanol extract was more active and exhibitinga broad spectrum antibacterial activity than the crude ethyl acetateextract against each of the bacterial strains tested. Maximum inhibitionzone (10.0 ± 0.1 mm) was observed against the gram negativePseudomonas aeruginosa in crude methanol extract. The consequentzone of 6.5 ± 0.1 mm was observed in ethyl acetate extract inP.aeruginosa.

Keywords: Microcosmus exasperatus, antimicrobial efficacy, zone of inhibition, urinary tract pathogens.

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