Abstract

FORMULATION AND DEVELOPMENT OF HERBAL CREAMS FOR BACTERIAL INFECTION

Jangme C. M*., Somnathe N. D., Kshirsagar M. D. and Shivakumar S. Ladde

ABSTRACT

Topical delivery can be defined as the application of a drug containing formulation to the skin to directly treat cutaneous disorder or the cutaneous manifestations of a general disease (eg:‐ psoriasis) with the intent of containing the pharmacological or the effect of drug to the surface of the skin or within the skin semi‐ solid formulations in all their diversity dominate the system for topical delivery, but foams, spray, medicated powders, solutions and even medicated adhesive systems are in use. Present aim of the work is Development and evaluation of efficacious and safe topical herbal drug delivery system for the treatment of Acne Vulgaris by using aqueous extracts of Azadirachta indica, Amba Haldi and Curcuma Longa for better efficacy, stability, sensory, and safety. Topical herbal formulation of the plant extract was evaluated for physical parameters, viscosity, Skin Irritation, Spreadibility and antimicrobial activity. The formulations were found to be better in all aspects. This preparation by use of herbal drugs leads to less expensive over the commercial available product. Thus it can be conferred that there is a growing demand for herbal cosmetics in the world market and they are invaluable gift of nature.

Keywords: Herbal Creams, White soft paraffin, Zone of inhibition, Skin Irritation.