TRANSDERMAL DRUG DELIVERY SYSTEM – A REVIEW
Nagappagari Madhuri*, E. Bhargav, Anand manne, V.Ravi, K.Ramesh
ABSTRACT
The human skin is a readily accessible surface for drug delivery. Over
the past three decades, developing controlled drug delivery has become
increasingly important in the pharmaceutical industry. Transdermal
drug delivery system is a formulation that is applied to the body
surface and is designed to deliver the active drug across the skin, into
the systemic circulation. Today about 74% of drugs are taken orally
and are found not to be as effective as desired. To improve such
characters trans dermal drug delivery system was emerged. Trans
dermal delivery offers several advantages over conventional routes
including avoidance of pre systemic and systemic first pass
metabolism, improved patient compliance, reduced side effects and controlled release over
extended period besides providing a convenient non-invasive delivery. This article deals with
a brief insight on the introduction, the formulation aspects, permeation enhancers and
evaluation aspects of transdermal drug delivery system explored to enhance the trans dermal
delivery of drugs across the stratum corneum.
Keywords: Transdermal drug delivery, Permeation enhancers, Stratum corneum.
[Download Article]
[Download Certifiate]