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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2020
Citation	6651	4087
h-index	26	21
i10-index	174	83

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2025 Issue has been successfully launched on 1 NOVEMBER 2025.

Abstract

DEVELOPMENT AND VALIDATION UV- VISIBLE SPECTROPHOTOMETRIC METHOD OF ESTIMATION OF TERBUTALIN SULPHATE IN BULK DRUG BY USING NINHYDRIN.

Shital Godse*, Gajanan A. Vaishnav, Sushama Vaishnav-Hota, Angadi S.S., Patil S. J.

ABSTRACT

An accurate, precise and simple spectrophotometric method for the determination of Terbutalin sulphate based on the formation of a yellow color product with Ninhydrin in the presence of sodium bicarbonate with an Î»max at 346 nm. The Reaction heating temperature is 80Â°c in 30 min. The calibration curve is linear over the range of 10-60 Î¼g/ml and the regression equation y=0.0263x+0.2with a regression coefficient (r) of 0.98 (n=10).The limit of Detection (LOD) and limit of Quantification (LOQ) calculated as per ICH guidelines are 18.15Î¼g/ml and 55Î¼g/ml, respectively.

Keywords: Terbutalin sulphate, UV-Spectrophotometer, Ninhydrin.

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