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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: APRIL ISSUE PUBLISHED

April Issue has been successfully launched on 1 April 2024.

Abstract

SYNTHESIS AND CHARACTERIZATION OF NOVEL 1,3-OXAZEPINE DERIVATIVES FROM AMINOPYRAZINE

Hawraa Mohammed Sadiq*

ABSTRACT

In this work new 1,3-oxazepine subsidiaries have been readied, by two stages: The initial step incorporate amino gathering of the 2-aminopyrazine was dense with various fragrant aldehydes within the sight of supreme ethanol to give novel Schiff bases subordinates [A1 – A5] separately. The second step, the subsequent imines subordinates [A1-A5] were responded with maleic anhydride and phathalic anhydride in dry toluene to give new 1,3-oxazepine-4,7-dione ring subsidiaries [B1a-B5a] and [B1b-B5b] individually scheme[I]. Every one of these mixes were described by liquefying focuses and FT.IR spectroscopy, several of them were portrayed by 1H-NMR spectroscopy and C.H.N. S. examination.

Keywords: Aminopyrazine, 1,3-Oxazepine, Schiff bases.

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