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Abstract

THE FLAVONOIDS AND ANTIMICROBIAL ACTIVITY OF DAUCUS SYRTICUS GROWING IN LIBYA

*Khaled A. Abdel Shafeek, Ali. M. Elsoll, Hamid M. Younis, Fatima M. AbdAlla, and Wael. M. ELsayed

ABSTRACT

Daucus syrticus is a wild plant common in the central zone of Libya, especially in Sirt region. Investigation of the flavonoidal constituents led to isolation and identification of three compounds from ethyl acetate fraction as: Luteolin, 7,4'- dimethoxy Luteolin and 6-hydroxy 4'-methoxy Apigenin. While Diosmetin-7-O-glucoide, Luteolin 3'- Oglucoside and 4'-methoxy Luteolin 7-O-rhamno-arabinoside were isolated from the butanol fraction of the methanolic extract . The structures of these flavonoids were characterized on the basis of their UV, NMR and MS spectroscopic data. The antimicrobial activity of different extracts and some of these compounds were tested against different microorganisms (bacteria and fungi). The results exhibited different degrees of inhibition against the tested microorganism.

Keywords: Apiaceae, Daucus syrticus, flavonoidal and antimicrobial activity.


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