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Dr. Kiran Jagtap, Dr. Ramesh Agarwal, Dr. Lata. Kale, Dr. Nilofar Zaidi, 5Dr. Sonia. Sodhi, Dr. ShaikhTauseeef Ahmed, Dr. Pratik.C. Parkarwar, Dr. Pooja. Muley, Dr. Syeda Shadab Farha and Dr. Pallavi. Ambhore


Oral lichen planus (OLP) is a determined inflammatory infection that affects the mucus membrane of the oral cavity. It is a T-cell mediated autoimmune disease in which the cytotoxic CD8+ T cells bring out apoptosis of the basal cells of the oral epithelium. Numerous antigen-specific and nonspecific inflammatory mechanisms have been put to the fore to explain the buildup and homing of CD8+ T cells subepithelially and the consequent keratinocyte apoptosis. In this review we are discussing about pathogenesis and treatment modalities of OLP.

Keywords: Apoptosis, autoimmune, basal keratinocytes, corticosteroids, oral lichen planus.

[Full Text Article]

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