Photo Gallery

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from  7.454 to 7.632  due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • WJPPS: SEPTEMBER ISSUE PUBLISHED
  • SEPTEMBER 2021 Issue has been successfully launched on 1 September 2021.

Abstract

CADD: PHARMACOLOGICAL APPROACHES IN DRUG DESIGN AND DRUG DISCOVERY

Dr. Siju E. N.*, Dr. G. R. Rajalakshmi, Anu P. Paulose, Fathima T., Dhanya P. P., Dr. N. Hariraj and K. Rahul

ABSTRACT

The objective of drug design is to find a chemical compound that can fit to a specific cavity on a protein target both geometrically and chemically. It is generally recognized that drug discovery and development are time and resources consuming processes. All the world‟s major pharmaceutical and biotechnology companies use computational design tools. At their lowest level the contributions represent the replacement of crude mechanical models by displays of structure which are a much more accurate reflection of molecular reality, capable of demonstrating motion and solvent effects. In recent years, the field of computer-aided drug design (CADD) has grown rapidly, enhancing our understanding of complex biological processes and protein-ligand interactions. CADD can predict experimental results with reasonable accuracy and reduced time, cost and equipment.

Keywords: Bioinformatics, CADD, molecular modeling, docking.


[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More