Abstract

AMLODIPINE INDUCED GINGIVAL ENLARGEMENT- A CASE REPORT

*Dr. Afroz Anjum, Dr. Mona Shah, Dr. Yogesh Doshi, Dr.Arush Shah, Dr. Pratik. C. Parkarwar, Dr. Vidhi Shah and Dr. Monika Bajaj

ABSTRACT

Healthy gums are pale pink or pigmented, which compactly envelop around the necks of the teeth. Gingival enlargement is an superfluous undesirable effect of some drugs such as cyclosporin, phenytoin and calcium channel antagonists.This can be a cosmetic problem, hinder with eating and speech, hamper effective tooth cleaning or force the teeth out of alignment. It is a serious concern for both the patient and the clinician due to unesthetic appearance and formation of new niches for periodonto-pathogenic bacteria. Antihypertensive drugs in the calcium channel blocker group are extensively used in elderly patients. Gingival enlargement associated with Nifedipine was first reported in 1980’s and is very rarely reported to be associated with Amlodipine and Felodipine. The mechanism through which these medications trigger a connective tissue response are still poorly understood. The most effective treatment of drug induced gingival overgrowth is withdrawl or substitution of medication combined with meticulous oral hygiene, plaque control, and removal of local irritants. When these measures fails to resolve the enlargement, surgical intervention is recommended. This case report a rare case of Amlodipine induced gingival enlargement.

Keywords: Amlodipine, Gingival Enlargement, Calcium channel blockers, Oral hygiene, local irritant, withdrawl.