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Abstract

ANTI-CANCER ACTIVITY OF MEMECYLON UMBELLATUM LEAF EXTRACT

Ravindra Puttaswamy, Peethambar SK,Vinayaka KS and RajeshwaraN Achur*

ABSTRACT

Memecylon umbellatum is an endemic plant from Western Ghats of Karnataka. The plant was successively extracted with solvents of different polarity (methanol and chloroform) and the extracts were analyzed for the anticancer activity in vitro. Methanol extract showed a very good activity (200μg/ml) compared to its counterpart on chloroform extract. The minimum inhibition of methanol extract was found to be 42% at 20μg/ml. Results of the study indicated a good anticancer activity of the methanol extract. Further work is in progress to isolate the novel compound of anticancer activity.

Keywords: Anti-cancer activity, Memecylon umbellatum, Plant extract, cytotoxicity.


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