WJPPS Citation

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • New Impact Factor
  • WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

  • WJPPS: MARCH ISSUE PUBLISHED
  • March Issue has been successfully launched on 1 March 2024.

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • Scope Indexed
  • WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

Abstract

ANTICANCER EFFICACY OF ROOT TISSUE AND ROOT-CALLUS OF ACANTHUS ILICIFOLIUS L., ON BENZO (A) PYRENE INDUCED PULMONARY CARCINOMA IN MUSMUSCULUS

*Chinnappan Ravinder Singh and KandasamyKathiresan

ABSTRACT

Acanthus ilicifoliusL. (Holly Mangroves) an important mangrove plant species wasstudied for anti-pulmonary carcinoma. The callus was raised from the root explants with the help of different growth regulators. Maximum callus biomass was observed in 3mg/L of 2,4-D. Shade dried root materials and in vitrocultured root callus were extracted with 9:1 ratio of chloroform and methanol. Then the partially purified compounds were subjectedto in vivoanti-pulmonary carcinoma. Pulmonary carcinoma was induced by benzo(a)pyrene. After 16 weeks of treatmentthe animals treated with root callus extract were completely recovered from lung cancer. The significant resultswere observed fromboth lung and liver tissues.The animals treated with root callus extract showed better result than the field grown root extract. The plant Acanthus ilicifoliusdid not show any toxic effect.In this present study,Acanthus ilicifolius was found to be a natural preventive source of pulmonary carcinoma.

Keywords: Pulmonary Carcinoma,Anti-cancer drug, Plant growth regulators and Antioxidantsoxidants.


[Download Article]     [Download Certifiate]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More