Photo Gallery

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from  7.454 to 7.632  due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • WJPPS MARCH ISSUE PUBLISHED
  • MARCH 2021 Issue has been successfully launched on 1 March 2021.

Abstract

FIRST ORDER DERIVATIVE SPECTROPHOTOMETRIC METHOD DEVELOPMENT AND VALIDATION FOR MIDODRINE HYDROCHLORIDE IN BULK AND TABLETS

Hemant K. Jain*, Kishor N. Gujar and Varsha A. Randhe

ABSTRACT

The objective of the study was to develop an UV spectrophotometric method for estimation of midodrine hydrochloride in bulk and tablets. First order derivative spectrophotometric method has been developed at wavelength 302.0 nm. Linearity was observed in the concentration range of 19.98-99.90 μg/ml. Low values of % RSD for intra-day and inter-day precision suggested reproducibility of the method. Satisfactory values of percent recovery indicated accuracy of the method. Sensitivity of the method was proved by low value of limit of detection and limit of quantitation. An assay result of marketed tablets was found to be 98.69%. The result suggest that the proposed methods were found to be cost effective, sensitive, precise and accurate and hence can be successfully applied for the routine analysis of Midodrine Hydrochloride in bulk and tablets.

Keywords: 10.20959/wjpps20167-7245


[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More