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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: APRIL ISSUE PUBLISHED

April Issue has been successfully launched on 1 April 2024.

Abstract

COLORIMETRIC METHODS FOR THE ESTIMATION OF TOPIRAMATE IN TABLETS

*P. G. Sunitha, R. Dhanalakshmi, A. Gangatharan, A. Kavi Bharathi, G. Murali Shankar and M. Sathya

ABSTRACT

Two simple sensitive and precise colorimetric methods A and B were developed for the estimation of topiramate in bulk drug as well as in pharmaceutical dosage form. Method A is based on the formation of purple coloured chromogen by diazotization and coupling reaction of topiramate with Bratton-Marshall reagent, which has absorption maximum at 551nm.Method B is based on the formation of an orange-red coloured complex with 1,10-Phenanthroline and ferric chloride which has absorption maximum at 508nm. The proposed methods are statistically validated and found to be useful for the routine determination of topiramate in tablets.

Keywords: Topiramate, Colorimetry, Tablets, Validation.

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