Abstract

EVALUATION OF ANTIMICROBIAL ACTIVITY OF NOTHAPODYTES NIMMONIANA (GRAHAM). ICACINACEAE

Uma.G*, Balasubramaniam. V and Jagathes Kumar. S

ABSTRACT

The present investigation was carried out to evaluate the antimicrobial activities of Nothapodytes nimmoniana. Dried leaf and stem powder of Nothapodytes nimmoniana was successively extracted with petroleum ether, chloroform, Acetone and methanol using Soxhlet. All extracts were screened for its antimicrobial activity using agar well disc diffusion method. The microorganisms used for antibacterial were Bacillus thuringiensis, Staphylococcus aureus, Escherichia coli, Serratia marcescens, Proteus vulgaris and Salmonella paratyphi. The microorganisms used for antifungal were Paecilomyces lilacinus, Mucur spp,Tricoderma viride, Azospirillum lipofererum, Verticillum lecanii, and Penicillium spp. The study confirms the antimicrobial activities of Nothapodytes nimmoniana leaves and stem extracted using various solvents, and is therefore, a potential drug that requires further studies and development.

Keywords: Antimicrobial Activity, Microorganisms, Agar well diffusion, Nothapodytes