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Abstract

NOVEL BENZIMIDAZOLE DERIVATIVES AS PARTIAL PPAR? AGONISTS: SYNTHESIS, CHARACTERIZATION AND DOCKING STUDIES

Gagandeep Singh, Amanjot Singh, Varinder Singh, Raman K. Verma and Rajiv Mall*

ABSTRACT

Synthetic and docking studies of novel benzimidazolyl linked para substituted benzylidene containing various hydrogen bonding parts viz thiazolidenedione (TZD), rhoadanine (RH), diethyl malonate (DEM), methyl acetoacetate (MAA), barbituric acid (BA) and thiobarbituric acid (TBA) as antidiabetic agents are reported.

Keywords: Benzimidazole, PPAR Partial agonists, Antidiabetics, Docking.


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