Photo Gallery

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from  7.454 to 7.632  due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • WJPPS: SEPTEMBER ISSUE PUBLISHED
  • SEPTEMBER 2021 Issue has been successfully launched on 1 September 2021.

Abstract

GUM ARABIC FOR MANUFACTURING OF HARD & SOFT EMPTY CAPSULE SHELL IN SUDAN

Dr. Suad Y. Alkarib*, Dr. Alkhair A. Khaleel and Dr. Mohamed A. Nurein

ABSTRACT

Introduction: Gum is a dried exudate from stems and branches of acacia seneglelinnewilldenow and other related African species of acacia Family Leguminosae. It is a safe non toxic material utilized in production of capsule shell compared to the gelatin. Capsule hardness and elasticity are influenced by changes in gum: water: plasticizer ratio. This study described the use of gum Arabic in the manufacturing of capsules, using water and plasticizer to fine-tune the elasticity. Methods: Hand pick gum Arabic grinded and treated by adding purified water and glycerin B.P, polyethylene B.P glycol, sorbitol in a ratio of 5:2:1 per volume in Wafrapharma industry. A flexible sheet was produced from the mucilage to confirm the formula reliability. Then after capsules shells were produced by process of dipping molds in the mucilage and let to dry. Results: The influence of gum: water: plasticizer ratio on capsule formulation showed the difference in ratio of gum solution formula affects the elasticity degree of the sheet. When the quantity of the plasticizer is increased, the ratio of water: plasticizer decreased. Conclusions: gum Arabic is a stable suitable natural material to be used in capsule shell production in Sudan. Both gum solution and plasticizer loading level were found to influence the initial rate of elasticity. Elasticity shown to be controlled by the added quantity of plasticizer.

Keywords: GumArabic, Acacia, Capsule shell and plasticizer.


[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More