Photo Gallery

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from  7.454 to 7.632  due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • WJPPS: SEPTEMBER ISSUE PUBLISHED
  • SEPTEMBER 2021 Issue has been successfully launched on 1 September 2021.

Abstract

PHARMACOKINETICS OF TILMICOSIN IN HEALTHY AND VACCINATED LACTATING GOATS. AND ITS EFFECT ON HUMORAL IMMUNE RESPONSE IN VACCINATED LACTATING GOATS.

Mossad Gamal El-Din Ahmed El Sayed, Ashraf Abd El-Hakim Ahmed El-Komy, Elham Ahmed Mobarez and Amir Ezzat Afify*

ABSTRACT

Tilmicosin was administered subcutaneously at a dose rate of 10 mg/kg. b.wt to determine its concentrations in blood as well as its kinetic behavior in healthy and vaccinated lactating goats. Tilmicosin was detectable in plasma for 72 hours. The mean peak plasma concentrations (Cmax) in healthy and vaccinated lactating goats were 1.07 ± 0.052 μg/ml, and 1.19 ± 0.043 μg/ml achieved at a maximum times (Tmax) of 1.91 ± 0.19 hour and 1.46 ± 0.24 hours, respectively. Tilmicosin significantly increase the antibody titer in vaccinated lactating goats when administrated at 21 days post vaccination with dose of 10 mg/kg. b.wt.

Keywords: Pharmacokinetics,Tilmicosin, Humoral immune response, Elisa, HPLC.


[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More