Photo Gallery



News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from  7.454 to 7.632  due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • SEPTEMBER 2021 Issue has been successfully launched on 1 September 2021.



Dr. N. B. Sridhara Murthy*, B. A. Sowmya and Manasa


To evaluate the Anti-ulcer activity of Betel wine with Cow urine by Aspirin induced ulcer model in rats. The leaves of Piper betel was dried under shade and then powdered and extracted with cow urine by maceration process and the resultant extract was subjected for phytochemical analysis to identify different phytoconstituents. An acute toxicity study of the extract was done up to 5000mg/kg according to OECD guidelines No 425. Histopathological changes of stomach were assessed for confirmation. Phytochemical investigation of Cow urine Betel vine extract revealed the presence of alkaloids, glycosides, flavonoids, saponins, carbohydrates, proteins, oils and fats. In acute toxicity studies Cow urine extract up to dose level of 5000mg/kg b.w did not revealed any variation in their physical observation or mortality, which indicates their nontoxic nature practically and safety of the extract. Based on the toxicity studies 250 and 500 mg/kg b.w was considered as the therapeutic dose as per the OECD guide lines. Oral administration of Cow urine Betel vine extract at the selected therapeutic doses showed dose related antiulcer activity in Aspirin induced ulcer model. The histopathological examination of the negative control treated stomach shows severe erosions of gastric mucosa, sub mucosal edema and neutrophil infiltration, which were absent in the extract and standard treated group.

Keywords: Piper betel, peptic ulcer, Aspirin.

[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More